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Clinical Trials

American Society of Hematology Meeting 2014: CMRG 001

First Report of the Myeloma Canada Research Network (MCRN)-001 Trial UtilizingBortezomib-Based Induction, Enhanced Conditioning with IV Busulfan + Melphalan(BuMel) and Lenalidomide Maintenance: Feasibility of a National Canadian Study Basedon Achievement of Minimal Residual Disease (MRD) Negativity

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American Society of Hematology Meeting 2015: CMRG 001

Myeloma Canada Research Network (MCRN)-001 Trial Utilizing Bortezomib (btz)-Based Induction, Enhanced Conditioning with IV Busulfan + Melphalan (BuMel) and Lenalidomide (len) Maintenance in Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplant (ASCT): A National Canadian Study Evaluating Achievement of Minimal Residual Disease (MRD) Negativity and Involved Serum Hevylite chain (HLC) Normalization

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International Myeloma Workshop Meeting 2015: CMRG 001

Myeloma Canada Research Network (MCRN) 001 Trial with Intravenous (IV) Busulfan + Melphalan (BuMel) as Enhanced Conditioning, followed by Lenalidomide (Len) Maintenance in Newly Diagnosed Multiple Myeloma (MM) Patients (Pts): First Results of Minimal Residual Disease (MRD) and Hevylite(TM) Chain (HLC) Assays at Day 100 Post Autologous Stem Cell Transplant (ASCT)

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American Society of Hematology Meeting 2016: CMRG 002

Selinexor in Combination with Bortezomib and Dexamethasone (SdB) Demonstrates Significant Activity in Patients with Refractory Multiple Myeloma (MM) Including Proteasome-Inhibitor Refractory Patients: Results of the Phase I Stomp Trial

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American Society of Hematology Meeting 2016: CMRG 001

Myeloma Canada Research Network (MCRN)-001 ASCT Study of Busulfan + Melphalan(BuMel) Conditioning Followed By Lenalidomide (Len) Maintenance: Updated ResultsIncluding Serial Minimal Residual Disease (MRD) and Involved Serum Hevyliteâ„¢ Chain(HLC) Ratio Assessments

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American Society of Hematology Meeting 2018: CMRG 003

A single arm phase II study of high-dose weekly Carfilzomib plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Myeloma after 1-3 prior therapies

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American Society of Hematology Meeting 2019: CMRG 004

A Randomized Phase II, Open Label, Study of Daratumumab, Weekly Low-Dose Oral Dexamethasone and Cyclophosphamide with or without Pomalidomide in Patients with Relapsed and Refractory Multiple Myeloma

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American Society of Hematology Meeting 2020: CMRG 004

A Randomized Phase II, Open Label, Study of Daratumumab, Weekly Low-Dose Oral Dexamethasone and Cyclophosphamide with or without Pomalidomide in Patients with Relapsed and Refractory Multiple Myeloma

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International Myeloma Workshop 2019: CMRG 007

The ALGONQUIN Study: A Phase 1/2 Multi-Center, Dose Escalation Study to Determine the RP2D, Safety and Efficacy of GSK2857916 in Combination with Pomalidomide and Low Dose Dexamethasone in Subjects with RRMM

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European Hematology Association Congress 2020: CMRG 007

Phase 1/2 Study of Belantamab mafodotin in Combination with Pomalidomide and Dexamethasone: Results for Part 1 Dose Finding

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American Society of Hematology Meeting 2020: CMRG 007

Part 1 Results of a Dose Finding Study of Belantamab Mafodotin in Combination with Pomalidomide and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM)

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International Myeloma Workshop 2021: CMRG 007

Extended Follow-Up Safety and Efficacy Results of Belantamab Mafodotin (Belamaf) 1.92 mg/kg or 2.5 mg/kg Combined with Pom and Dex for the Treatment of Relapsed/Refractory Multiple Myeloma

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International Myeloma Workshop 2019: CMRG 009

Initial Results of MCRN 009: Phase 2 Study of an Accelerated Infusion Rate of Daratumumab in Patients with Relapsed/Refractory Multiple Myeloma (MM)

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Real-World Evidence

European Hematology Association Meeting 2018

The Myeloma Canada Research Network Canadian Multiple Myeloma Database (MCRN CMM-DB): Multi-Institutional Sharing Of Clinical Data For Research

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American Society of Hematology Meeting 2018

Real-world outcomes with bortezomib-containing regimens and lenalidomide and dexamethasone for the treatment of transplant ineligible MM patients: A multi-institutional report from the National Myeloma Canada Research Network (MCRN) database

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European Journal of Hematology Vol. 105 Issue 5: May 2021

The impact of lenalidomide maintenance on second-line chemotherapy in transplant eligible patients with multiple myeloma

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Haematologica Vol. 106 No. 6: June, 2021

The survival impact of maintenance lenalidomide: an analysis of real-world data from the Canadian Myeloma Research Group national database

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Journal of Cancer Immunology Vol. 3 Issue 1: 2021

Lenalidomide Maintenance After Autologous Stem Cell Transplant: The Utility of Real-World Data and Future Areas of Study

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British Journal of Haematology Vol. 193 Issue 3: May 2021

Real-world outcomes with bortezomib-containing regimens and lenalidomide plus dexamethasone for the treatment of transplant-ineligible multiple myeloma: a multi-institutional report from the Canadian Myeloma Research Group database

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European Hematology Association Meeting 2019

Lenalidomide maintenance positively impacts outcomes in multiple myeloma without negative impacts in relapse: An analysis of Real World Data from the Myeloma Canada Research Network National Database

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International Myeloma Workshop 2019

The impact of lenalidomide maintenance on second line chemotherapy in transplant eligible patients with multiple myeloma in the Canadian setting

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American Society of Hematology Meeting 2019

Treatment of myeloma patients progressing on lenalidomide-based maintenance after ASCT performed as part of 1st, 2nd or 3rd line therapy: Real-World results from the National Myeloma Canada Research Network Database

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European Hematology Association Meeting 2019

Treatment of multiple myeloma patients progressing on lenalidomide-based regimens

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American Society of Hematology Meeting 2020

Efficacy of daratumumab containing regimens post lenalidomide maintenance in transplant eligible patients: Real-World Experience from the Canadian Myeloma Research Group Database

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American Society of Hematology Meeting 2020

Sequential use of carfilzomib and pomalidomide in relapsed multiple myeloma: A multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database

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American Society of Hematology Meeting 2020

Maintenance therapy but not tandem autologous stem cell transplant (ASCT) improves outcomes in multiple myeloma with high-risk cytogenetics: Results from the Canadian Myeloma Research Group (CMRG) Database

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American Society of Hematology Meeting 2020

Efficacy of daratumumab containing regimens post lenalidomide maintenance in transplant eligible patients: Real-World Experience from the Canadian Myeloma Research Group Database

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American Society of Hematology Meeting 2020

Sequential use of carfilzomib and pomalidomide in relapsed multiple myeloma: A multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database

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European Hematology Association Meeting 2021

Carfilzomib-containing regimens for relapsed multiple myeloma in a Real-World setting: A multi-institutional report from the Canadian Myeloma Research Group (CMRG)

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European Hematology Association Meeting 2021

Survival and outcomes of newly-diagnosed multiple myeloma patients stratified by transplant status diagnosed between 2007-2018: Real-World analysis from the Canadian Myeloma Research Group Database

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European Hematology Association Meeting 2021

Outcomes of daratumumab-containing regimens in the treatment of relapsed multiple myeloma: Real-World data from the Canadian Myeloma Research Group Database

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European Journal of Haematology Vol. 107 Issue 4: October 2021

Retrospective study of treatment patterns and outcomes post-lenalidomide for multiple myeloma in Canada

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